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Objective To evaluate the risk model of patients with secondary end stage renal disease (ESRD),and to validate its applicability by collecting clinical parameters of contrast induced nephropathy (CIN).Methods CIN patients were continuously enrolled in the study.The clinical data and laboratory results were analyzed.Eighteen months follow-up was performed for CIN patients to confirm the prognosis,and the long-term risk prediction and related risk assessment were analyzed based on the follow-up results.Results Totally 215 cases of CIN patients were included in the study.Among them,14 patients were lost in follow-up,and 19 patients progressed to ESRD stage during follow-up period.Cox regression analysis showed that the risk factors of poor prognosis in CIN patients included repeated angiography,high MRS scale score,high uKIM-1 level,high umAlb level and high uNGAL level.All of these factors were independent risk factors of ESRD within 18 months in CIN patients.Taking umAlb=36.80 ng/ml,uNGAL=128.21 ng/ml,uKIM-1=137.56 pg/ml as threshold,the areas under ROC curve were 0.746,0.756 and 0.768 respectively.Conclusion In this study,the risk factors of ESRD in CIN patients were predicted and quantified,and the CIN diagnosis and treatment system were further improved.
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Objective To compare the diagnostic efficacy of digital mammography,ultrasonography and MRI for breast non-mass enhancement (NME).Methods The digital mammography,ultrasonography and MRI data of 1 1 6 patients with 123 NME lesions on MRI were analyzed retrospectively.Results 99 lesions were malignant and 24 lesions were benign according to the pathologiacl result.The sensitivity of digital mammography,ultrasonography and MRI was 72.73%,65.66%,and 84.85%,respectively;The specificity was 66.67%,79.1 7%,and 79.1 7%,respectively;The accuracy was 71.54%,68.29%,and 83.74%,respectively;The positive pretictive value was 90.00%,92.86%,and 94.88%,respectively;The negative pretictive value was 37.21%,35.85%,and 55.88%,respectively.The sensitivity,specificity,accuracy,positive pretictive value and negative pretictive value of MRI were obviously higher than those of digital mammography and ultrasonography (P <0.05).The difference between the combinations and MRI alone were no statistically significant.Conclusion MRI have better diagnostic value,and could be used as the first choice examination for breast NME lesions.
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Objective To study the application of super-selective external carotid artery embolization in head and neck diseases. Methods DSA and super-selective external carotid artery embolization were carried out in 41 cases of head and neck diseases including 12 cases of epistaxis,7 nasopharyngeal fibroangioma,1 traumatic arterial bleeding,14 vascular malformation,and 7 malignancies. Results No recurrence of nose bleeding after embolization of epistaxis was seen within 6 - 12-month follow up. The operative bleeding was reduced significantly by preoperative embolization in nasopharyngeal fibroangioma. No recurrence of bleeding was achieved after embolization of traumatic artery. Among the cases of vascular malformation,3 were proven to be significantly effcient,6 effcient,and 5 inefficent in the 6 - 12-month follow up. Among the 7 malignant cases,3 survived more than 2 years. Conclusion Super-selective external carotid artery embolization is safe and effective in the treatment of head and neck diseases. (J Intervent Radiol,2006,15: 330-332)